Ok i would like to know the best way that i could get the best out of my amp and my subs , can someone help ?

I have two 12" dual voice coil, 4 ohm memphis subwoofers. Each one of them are 250w rms - 500w peak. And I have a Rockford Fosgate r500-1 class a/b mono block amplifier. It is rated at 500rms at 2ohms and 350 rms at 4ohms. Can anyone please tell me how I would wire the subs to my amp, and how to wire my coils, eaither in parallel or series.. a diagram would really help. And also i need help on how to set my gains on my amp..